Example single dose Theophylline ODE model
This is a nlmixr2 model that is pre-run so that it can be used in package testing and development. It is regenerated whenever binaries of nlmixr2extra are created. If there is a binary incompatability between the fit objects, a simple rerun of the installation will fix this nlmixr2 fit object.
Format
A (modified) data frame with 132 rows and 22 columns.
- ID: Patient identifier
- TIME: Time (hr)
- DV: Dependent variable (concentration)
- PRED: Predictions without any between subject variability
- RES: Population Residual
- WRES: Weighted Residuals under the FO assumption
- IPRED: Individual Predictions
- IRES: Individual Residuals
- IWRES: Individual Weighted Residuals
- CPRED: Conditional Prediction under the FOCE assumption
- CRES: Conditional Residuals under the FOCE assumption
- CWRES: Conditional Weighted Residuals under the FOCE assumption
- eta.ka: Between subject changes for ka
- eta.cl: Between subject changes for v
- depot: amount in the depot compartment
- center: amount in the central compartment
- ka: Individual ka values
- cl: Individual cl values
- v: Individual volume of distribution
- tad: Time after dose
- dosenum: Dose number