# GGM Compare: Posterior Predictive Check Compare GGMs with a posterior predicitve check \insertCite gelman1996posteriorBGGM. This method was introduced in \insertCite williams2020comparing;textualBGGM. Currently, there is a `global` (the entire GGM) and a `nodewise` test. The default is to compare GGMs with respect to the posterior predictive distribution of Kullback Leibler divergence and the sum of squared errors. It is also possible to compare the GGMs with a user defined test-statistic. ```r ggm_compare_ppc( ..., test = "global", iter = 5000, FUN = NULL, custom_obs = NULL, loss = TRUE, progress = TRUE ) ``` ## Arguments - `...`: At least two matrices (or data frames) of dimensions **n** (observations) by **p** (variables). - `test`: Which test should be performed (defaults to `"global"`) ? The options include `global` and `nodewise`. - `iter`: Number of replicated datasets used to construct the predictivie distribution (defaults to 5000). - `FUN`: An optional function for comparing GGMs that returns a number. See Details . - `custom_obs`: Number corresponding to the observed score for comparing the GGMs. This is required if a function is provided in `FUN`. See Details . - `loss`: Logical. If a function is provided, is the measure a "loss function" (i.e., a large score is bad thing). This determines how the **p**-value is computed. See Details . - `progress`: Logical. Should a progress bar be included (defaults to `TRUE`) ? ## Returns The returned object of class `ggm_compare_ppc` contains a lot of information that is used for printing and plotting the results. For users of BGGM , the following are the useful objects: `test = "global"` * `ppp_jsd` posterior predictive **p**-values (JSD). * `ppp_sse` posterior predictive **p**-values (SSE). * `predictive_jsd` list containing the posterior predictive distributions (JSD). * `predictive_sse` list containing the posterior predictive distributions (SSE). * `obs_jsd` list containing the observed error (JSD). * `obs_sse` list containing the observed error (SSE). `test = "nodewise"` * `ppp_jsd` posterior predictive **p**-values (JSD). * `predictive_jsd` list containing the posterior predictive distributions (JSD). * `obs_jsd` list containing the observed error (JSD). `FUN = f()` * `ppp_custom` posterior predictive **p**-values (custom). * `predictive_custom` posterior predictive distributions (custom). * `obs_custom` observed error (custom). ## Details The `FUN` argument allows for a user defined test-statisic (the measure used to compare the GGMs). The function must include only two agruments, each of which corresponds to a dataset. For example, `f <- function(Yg1, Yg2)`, where each Y is dataset of dimensions **n** by **p**. The groups are then compare within the function, returning a single number. An example is provided below. Further, when using a custom function care must be taken when specifying the argument `loss`. We recommended to visualize the results with `plot` to ensure the **p**-value was computed in the right direction. ## Note Interpretation : The primary test-statistic is symmetric KL-divergence that is termed Jensen-Shannon divergence (JSD). This is in essence a likelihood ratio that provides the "distance" between two multivariate normal distributions. The basic idea is to (1) compute the posterior predictive distribution, assuming group equality (the null model). This provides the error that we would expect to see under the null model; (2) compute JSD for the observed groups; and (3) compare the observed JSD to the posterior predictive distribution, from which a posterior predictive **p**-value is computed. For the `global` check, the sum of squared error is also provided. This is computed from the partial correlation matrices and it is analagous to the strength test in \insertCite van2017comparing;textualBGGM. The `nodewise` test compares the posterior predictive distribution for each node. This is based on the correspondence between the inverse covariance matrix and multiple regresssion \insertCite kwan2014regression,Stephens1998BGGM. If the null model is `not` rejected, note that this does `not` provide evidence for equality! Further, if the null model is rejected, this means that the assumption of group equality is not tenable--the groups are different. Alternative Methods : There are several methods in BGGM for comparing groups. See `ggm_compare_estimate` (posterior differences for the partial correlations), `ggm_compare_explore` (exploratory hypothesis testing), and `ggm_compare_confirm` (confirmatory hypothesis testing). ## Examples ```r # note: iter = 250 for demonstrative purposes # data Y <- bfi ############################# ######### global ############ ############################# # males Ym <- subset(Y, gender == 1, select = - c(gender, education)) # females Yf <- subset(Y, gender == 2, select = - c(gender, education)) global_test <- ggm_compare_ppc(Ym, Yf, iter = 250) global_test ############################# ###### custom function ###### ############################# # example 1 # maximum difference van Borkulo et al. (2017) f <- function(Yg1, Yg2){ # remove NA x <- na.omit(Yg1) y <- na.omit(Yg2) # nodes p <- ncol(Yg1) # identity matrix I_p <- diag(p) # partial correlations pcor_1 <- -(cov2cor(solve(cor(x))) - I_p) pcor_2 <- -(cov2cor(solve(cor(y))) - I_p) # max difference max(abs((pcor_1[upper.tri(I_p)] - pcor_2[upper.tri(I_p)]))) } # observed difference obs <- f(Ym, Yf) global_max <- ggm_compare_ppc(Ym, Yf, iter = 250, FUN = f, custom_obs = obs, progress = FALSE) global_max # example 2 # Hamming distance (squared error for adjacency) f <- function(Yg1, Yg2){ # remove NA x <- na.omit(Yg1) y <- na.omit(Yg2) # nodes p <- ncol(x) # identity matrix I_p <- diag(p) fit1 <- estimate(x, analytic = TRUE) fit2 <- estimate(y, analytic = TRUE) sel1 <- select(fit1) sel2 <- select(fit2) sum((sel1$adj[upper.tri(I_p)] - sel2$adj[upper.tri(I_p)])^2) } # observed difference obs <- f(Ym, Yf) global_hd <- ggm_compare_ppc(Ym, Yf, iter = 250, FUN = f, custom_obs = obs, progress = FALSE) global_hd ############################# ######## nodewise ########## ############################# nodewise <- ggm_compare_ppc(Ym, Yf, iter = 250, test = "nodewise") nodewise ``` ## References \insertAllCited

ggm_compare_ppc function