C_sampling_cluster function

cis-Regulatory Module Sampling Function

Function 'C_sampling_cluster' samples a candidate cis-regulatory module for each gene, according to a discrete posterior probability distribution.

C_sampling_cluster(Y, C_old, A_old, X_old, base_line_old, C_prior, sigma_noise,
  sigma_A, sigma_baseline, sigma_X, BICORN_input)

Arguments

• Y: gene expression data matrix
• C_old: TF-gene binding network sampled from the previous round
• A_old: regulatory strength matrix sampled from the previous round
• X_old: transcription factor activity matrix sampled from the previous round
• base_line_old: gene expression baseline activity sampled from the previous round
• C_prior: prior TF-gene binding network
• sigma_noise: variance of gene expression fitting residuals
• sigma_A: variance of regulatory strength
• sigma_baseline: variance of gene expression baseline activity
• sigma_X: variance of transcription factor activity
• BICORN_input: this list structure contains TF symbols, Gene symbols and candidate modules