baseline_sampling function

Gene Baseline Expression Sampling Function

Function 'baseline_sampling' estimates a baseline expression for each gene, according to a posterior Gaussian distribution.

baseline_sampling(Y, C, A, X, base_line_old, C_prior, sigma_noise, sigma_A,
  sigma_baseline, sigma_X)

Arguments

• Y: gene expression data matrix
• C: sampled TF-gene binding network
• A: sampled regulatory strength matrix
• X: sampled transcription factor activity matrix
• base_line_old: prior gene expression baseline activity
• C_prior: prior TF-gene binding network
• sigma_noise: variance of gene expression fitting residuals
• sigma_A: variance of regulatory strength
• sigma_baseline: variance of gene expression baseline activity
• sigma_X: variance of transcription factor activity