BuyseTest3.0.4 package

Generalized Pairwise Comparisons

iid.BuyseTestBrier

Extract the idd Decomposition for the Brier Score

simBuyseTest

Simulation of data for the BuyseTest

simCompetingRisks

Simulation of Gompertz competing risks data for the BuyseTest

summary.performance

Summary Method for Performance Objects

as.data.table.performance

Convert Performance Objet to data.table

auc

Estimation of the Area Under the ROC Curve (EXPERIMENTAL)

autoplot-S4BuyseTest

Graphical Display for GPC

brier

Estimation of the Brier Score (EXPERIMENTAL)

BuyseMultComp

Adjustment for Multiple Comparisons

BuyseTest-package

BuyseTest package: Generalized Pairwise Comparisons

BuyseTest.options-class

Class "BuyseTest.options" (global setting for the BuyseTest package)

BuyseTest.options-methods

Methods for the class "BuyseTest.options"

BuyseTest.options

Global options for BuyseTest package

BuyseTest

Two-group GPC

BuyseTTEM

Time to Event Model

calcIntegralSurv2_cpp

C++ Function pre-computing the Integral Terms for the Peron Method in ...

CasinoTest

Multi-group GPC (EXPERIMENTAL)

coef.BuyseTestAuc

Extract the AUC Value

coef.BuyseTestBrier

Extract the Brier Score

confint.BuyseTestAuc

Extract the AUC value with its Confidence Interval

confint.BuyseTestBrier

Extract the Brier Score with its Confidence Interval

constStrata

Strata creation

dot-calcIntegralCif_cpp

C++ Function Computing the Integral Terms for the Peron Method in the ...

dot-calcIntegralSurv_cpp

C++ Function Computing the Integral Terms for the Peron Method in the ...

dot-colCenter_cpp

Substract a vector of values in each column

dot-colCumSum_cpp

Column-wise cumulative sum

dot-colMultiply_cpp

Multiply by a vector of values in each column

dot-colScale_cpp

Divide by a vector of values in each column

dot-rowCenter_cpp

Substract a vector of values in each row

dot-rowCumProd_cpp

Apply cumprod in each row

dot-rowCumSum_cpp

Row-wise cumulative sum

dot-rowMultiply_cpp

Multiply by a vector of values in each row

dot-rowScale_cpp

Dividy by a vector of values in each row

GPC_cpp

C++ function performing the pairwise comparison over several endpoints...

iid.BuyseTestAuc

Extract the idd Decomposition for the AUC

iid.prodlim

Extract i.i.d. decomposition from a prodlim model

performance

Assess Performance of a Classifier

performanceResample

Uncertainty About Performance of a Classifier (EXPERIMENTAL)

plot-sensitivity

Graphical Display for Sensitivity Analysis

powerBuyseTest

Performing simulation studies with BuyseTest

predict.BuyseTTEM

Prediction with Time to Event Model

rbind.performance

Combine Resampling Results For Performance Objects

S4BuysePower-class

Class "S4BuysePower" (output of BuyseTest)

S4BuysePower-model.tables

Extract Summary for Class "S4BuysePower"

S4BuysePower-nobs

Sample Size for Class "S4BuysePower"

S4BuysePower-print

Print Method for Class "S4BuysePower"

S4BuysePower-summary

Summary Method for Class "S4BuysePower"

S4BuyseTest-class

Class "S4BuyseTest" (output of BuyseTest)

S4BuyseTest-coef

Extract Summary Statistics from GPC

S4BuyseTest-confint

Extract Confidence Interval from GPC

S4BuyseTest-getCount

Extract the Number of Favorable, Unfavorable, Neutral, Uninformative p...

S4BuyseTest-getIid

Extract the H-decomposition of the Estimator

S4BuyseTest-getPairScore

Extract the Score of Each Pair

S4BuyseTest-getPseudovalue

Extract the pseudovalues of the Estimator

S4BuyseTest-getSurvival

Extract the Survival and Survival Jumps

S4BuyseTest-model.tables

Extract Summary for Class "S4BuyseTest"

S4BuyseTest-nobs

Sample Size for Class "S4BuyseTest"

S4BuyseTest-plot

Graphical Display for GPC

S4BuyseTest-print

Print Method for Class "S4BuyseTest"

S4BuyseTest-sensitivity

Sensitivity Analysis for the Choice of the Thresholds

S4BuyseTest-show

Show Method for Class "S4BuysePower"

S4BuyseTest-summary

Summary Method for Class "S4BuyseTest"

validFCTs

Check Arguments of a function.

Implementation of the Generalized Pairwise Comparisons (GPC) as defined in Buyse (2010) <doi:10.1002/sim.3923> for complete observations, and extended in Peron (2018) <doi:10.1177/0962280216658320> to deal with right-censoring. GPC compare two groups of observations (intervention vs. control group) regarding several prioritized endpoints to estimate the probability that a random observation drawn from one group performs better than a random observation drawn from the other group (Mann-Whitney parameter). The net benefit and win ratio statistics, i.e. the difference and ratio between the probabilities relative to the intervention and control groups, can then also be estimated. Confidence intervals and p-values are obtained based on asymptotic results (Ozenne 2021 <doi:10.1177/09622802211037067>), non-parametric bootstrap, or permutations. The software enables the use of thresholds of minimal importance difference, stratification, non-prioritized endpoints (O Brien test), and can handle right-censoring and competing-risks.

  • Maintainer: Brice Ozenne
  • License: GPL-3
  • Last published: 2024-07-01