Bayesian Meta Analysis for Studying Cross-Phenotype Genetic Associations
Analytic calculation of the local FDR & Bayes factor for correlated su...
Analytic calculation of the local FDR & Bayes factor for uncorrelated ...
CPBayes: An R-package implemeting a Bayesian meta analysis method for ...
Run correlated version of CPBayes.
Run uncorrelated version of CPBayes.
Estimate correlation structure of beta-hat vector for multiple overlap...
Forest plot presenting pleiotropy result obtained by CPBayes.
Post summary of the MCMC data generated by the uncorrelated or correla...
A Bayesian meta-analysis method for studying cross-phenotype genetic associations. It uses summary-level data across multiple phenotypes to simultaneously measure the evidence of aggregate-level pleiotropic association and estimate an optimal subset of traits associated with the risk locus. CPBayes is based on a spike and slab prior. The methodology is available from: A Majumdar, T Haldar, S Bhattacharya, JS Witte (2018) <doi:10.1371/journal.pgen.1007139>.
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