Simultaneous Detection of Clusters and Cluster-Specific Genes in High-Throughput Transcriptome Data
Performs simultaneous detection of cell types and cell-type-specific s...
Gene Filter
Plots the results of ClussCluster
Plots the results of ClussCluster_Gap
Prints out the results of ClussCluster
Prints out the results of ClussCluster_Gap
Prints the gap statistics ...
Implements a new method 'ClussCluster' descried in Ge Jiang and Jun Li, "Simultaneous Detection of Clusters and Cluster-Specific Genes in High-throughput Transcriptome Data" (Unpublished). Simultaneously perform clustering analysis and signature gene selection on high-dimensional transcriptome data sets. To do so, 'ClussCluster' incorporates a Lasso-type regularization penalty term to the objective function of K- means so that cell-type-specific signature genes can be identified while clustering the cells.