Fitting mixed models with known covariance structures.
The main functions are emmreml, and emmremlMultiKernel.emmreml solves a mixed model with known covariance structure using the EMMA algorithm in Kang et.al. (2008). emmremlMultiKernel is a wrapper for emmreml to handle multiple random components with known covariance structures. The function emmremlMultivariate solves a multivariate gaussian mixed model with known covariance structure using the ECM algorithm in Zhou and Stephens (2012). package
| Package: | EMMREML |
| Type: | Package |
| Version: | 3.1 |
| Date: | 2015-07-20 |
| License: | GPL-2 |
Deniz Akdemir, Okeke Uche Godfrey
Maintainer: Deniz Akdemir deniz.akdemir.work@gmail.com
Efficient control of population structure in model organism association mapping. Kang, Hyun Min and Zaitlen, Noah A and Wade, Claire M and Kirby, Andrew and Heckerman, David and Daly, Mark J and Eskin, Eleazar. Genetics, 2008.
Genome-wide efficient mixed-model analysis for association studies. Zhou, Xiang and Stephens, Matthew. Nature genetics, 2012.
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