est_mixture_wgs function

It is a function that takes the count data obtained from whole genome sequencing (WGS) data and returns the estimated tumor and normal proportions. Currently, the function can performs the proportion estimations by assuming the number of tumor clones to be 1 or 2. The normalization step is not required and the normalization constant will be returned by this function. The function will output two sets of solutions corresponding to the top 2 optimal solutions based on the posterior distribution. You can choose according to your expertise the one that is more reasonable.

  • Maintainer: Xuan You
  • License: GPL (>= 2)
  • Last published: 2018-09-13

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