High-Dimensional Mediation Analysis
Classic high-dimensional mediation analysis
High-dimensional mediation analysis with de-biased lasso penalty
Efficient high-dimensional mediation analysis
High-Dimensional Mediation Analysis for 'Omic' Data
High-dimensional Mediation Analysis
High-dimensional mediation analysis for compositional microbiome data
High-dimensional quantile mediation analysis
High-dimensional mediation analysis for survival data
Allows to estimate and test high-dimensional mediation effects based on advanced mediator screening and penalized regression techniques. Methods used in the package refer to Zhang H, Zheng Y, Zhang Z, Gao T, Joyce B, Yoon G, Zhang W, Schwartz J, Just A, Colicino E, Vokonas P, Zhao L, Lv J, Baccarelli A, Hou L, Liu L. Estimating and Testing High-dimensional Mediation Effects in Epigenetic Studies. Bioinformatics. (2016) <doi:10.1093/bioinformatics/btw351>. PMID: 27357171.