HTSSIP1.4.1 package

High Throughput Sequencing of Stable Isotope Probing Data Analysis

as.Num

conversion to numeric

BD_shift

Assessing the magnitude of BD shifts with 16S rRNA community data by c...

calc_atom_excess

Calculate atom fraction excess

calc_Gi

Calculate G+C from unlabeled buoyant density

calc_Mheavymax

Calculate the theoretical maximum molecular weight of fully-labeled DN...

data-physeq_rep3

(Data) A simulated HTS-SIP dataset

data-physeq_rep3_qPCR

(Data) qPCR data associated with the physeq_rep3 HTS-SIP dataset

data-physeq_S2D1

(Data) A subset of full HTS-SIP dataset (Substrates=2, Days=1)

data-physeq_S2D1_l

(Data) A subset of full HTS-SIP dataset (Substrates=2, Days=1)

data-physeq_S2D2

(Data) A subset of full HTS-SIP dataset (Substrates=2, Days=2)

data-physeq_S2D2_l

(Data) A subset of full HTS-SIP dataset (Substrates=2, Days=2)

delta_BD

delta_BD calculation

DESeq2_l2fc

Calculating log2 fold change for HTS-SIP data.

evaluate_matches

Evaluate String Interpolation Matches

expr_param_extract

Extract all quoted values in the expression used for phyloseq subsetti...

extract_expressions

Extract Expression Objects from String Interpolation Matches

extract_formats

Extract String Interpolation Formats from Matched Placeholders

filter_l2fc

Filter l2fc table

format_metadata

Format phyloseq metadata for calculating BD range overlaps.

fraction_overlap

Calculate the BD range overlap of gradient fractions

get_treatment_params

Get parameters for subsetting the phyloseq dataset

gradient_sim

Simulate HTS-SIP communities for 1 density gradient

heavy_SIP

Heavy-SIP analysis

HRSIP

(MW-)HR-SIP analysis

HTSSIP

HTSSIP: analyzing high throughput sequence data from nucleotide stable...

HTSSIP_sim

Simulate a HTS-SIP dataset

match_brace

Utility Function for Matching a Closing Brace

match_placeholders

Match Expression Placeholders for String Interpolation

max_BD_range

Adjusting BD range size if negative.

OTU_qPCR_trans

Transform OTU counts based on qPCR data

overlap_wmean_dist

Calculating weighted mean beta-diversities of overlapping gradient fra...

parse_dist

Filtering out non-relevant distances in distance matrix

perc_overlap

Calculate the percent overlap between two ranges (x & y).

phyloseq_list_ord_dfs

Converting ordination objects to data.frames

phyloseq_ord_plot

Plotting beta diversity ordination

phyloseq_subset

Make a list of phyloseq object subsets

phyloseq2df

phyloseq data object conversion to data.frame

phyloseq2table

Phyloseq conversion to a ggplot-formatted table

physeq_format

Checking format of phyloseq object for HTSSIP compatibility

physeq_list_betaDiv

calculating beta diversity for a list of phyloseq objects

physeq_list_ord

calculating ordinations from a list of distance matrices

qPCR_sim

Simulate qPCR values

qSIP_atom_excess

Calculate atom fraction excess using q-SIP method

qSIP_atom_excess_format

Reformat a phyloseq object of qSIP_atom_excess analysis

qSIP_bootstrap

Calculate bootstrap CI for atom fraction excess using q-SIP method

SIP_betaDiv_ord

Calculating & plotting beta diversity for a list of phyloseq objects

stringterpolate

String Interpolation

tss

Total sum scaling

Functions for analyzing high throughput sequencing stable isotope probing (HTS-SIP) data. Analyses include high resolution stable isotope probing (HR-SIP), multi-window high resolution stable isotope probing (MW-HR-SIP), and quantitative stable isotope probing (q-SIP).

  • Maintainer: Samuel Barnett
  • License: GPL-2 | file LICENSE
  • Last published: 2019-09-13