A Predictive Haplotyping Package
Auto Locus - An Automated Pipeline for Locus Prediction
Haplotype Prediction: Cross Validation of KNN and RF Models
Haplotype Prediction: Permutation Cross Validation of KNN and RF Model...
Haplotype Prediction: Using Trained Models to Make Predictions
Haplotype Prediction: Training Models for Use in Forward Prediction
Visualize Permutation CV Results
Used for predicting a genotype’s allelic state at a specific locus/QTL/gene. This is accomplished by using both a genotype matrix and a separate file which has categorizations about loci/QTL/genes of interest for the individuals in the genotypic matrix. A training population can be created from a panel of individuals who have been previously screened for specific loci/QTL/genes, and this previous screening could be summarized into a category. Using the categorization of individuals which have been genotyped using a genome wide marker platform, a model can be trained to predict what category (haplotype) an individual belongs in based on their genetic sequence in the region associated with the locus/QTL/gene. These trained models can then be used to predict the haplotype of a locus/QTL/gene for individuals which have been genotyped with a genome wide platform yet not genotyped for the specific locus/QTL/gene. This package is based off work done by Winn et al 2021. For more specific information on this method, refer to <doi:10.1007/s00122-022-04178-w>.