ISOpureS1.model_optimize.kappa.kappa_compute_loglikelihood function

Compute loglikelihood relevant to kappa for step 1

Computes the part of the loglikelihood function relevant to optimizing kappa for step 1

ISOpureS1.model_optimize.kappa.kappa_compute_loglikelihood(kappa, tumordata, model)

Arguments

• kappa: a scalar kappa, the strength parameter in the prior over the reference cancer profile
• tumordata: a GxD matrix representing gene expression profiles of tumour samples
• model: list containing all the parameters to be optimized

Returns

The part of the loglikelihood function relevant to optimizing kappa

Author(s)

Gerald Quon, Catalina Anghel, Francis Nguyen