ISOpureS1.model_optimize.mm.mm_loglikelihood function

Compute the loglikelihood relevant to mm for step 1

Computes the loglikelihood function relevant to optimizing the reference cancer profile, mm, for step 1

ISOpureS1.model_optimize.mm.mm_loglikelihood(ww, tumordata, model)

Arguments

• ww: the mm_weights, with G entries
• tumordata: a GxD matrix representing gene expression profiles of tumor samples
• model: list containing all the parameters to be optimized

Returns

The negative of the likelihood function relevant to optimizing mm.

Author(s)

Gerald Quon, Catalina Anghel, Francis Nguyen