ISOpureS2.model_optimize.cc.cc_loglikelihood function

Compute the loglikelihood relevant to the patient cancer profiles, cc, for step 2

Computes the part of the loglikelihood function relevant to optimizing cc for patient dd, the cancer profile for that patient

ISOpureS2.model_optimize.cc.cc_loglikelihood(ww, tumordata, dd, model)

Arguments

• ww: the cc_weights for patient dd, with G entries
• tumordata: a GxD matrix representing gene expression profiles of tumor samples
• dd: the patient number
• model: list containing all the parameters to be optimized

Returns

The negative the part of the loglikelihood function relevant to optimizing cc for patient dd, the cancer profile for that patient.

Author(s)

Gerald Quon, Catalina Anghel, Francis Nguyen