cov_adj function

Adjust omic blocks for covariates effects.

This function is called by moss to adjust a series of omic blocks for covariates effects. However, if the covariates object is too big, the user is recommended to call cov_adj ahead of moss.

cov_adj(data.blocks, covs, n, dim.names = NULL)

Arguments

• data.blocks: List containing omic blocks of class 'matrix' or 'FBM'. In each block, rows represent subjects and columns features.
• covs: Covariates which effect we wish to adjust for. Accepts objects of class matrix, data.frame, numeric, or character vectors.
• n: Number of subjects. Numeric.
• dim.names: list of vectors with samples names, and features names by omic block. If NULL, a list of artificial names is created. Defaults to NULL.

Returns

Returns the covariates-adjusted elements in data.blocks.

Examples

library("MOSS")
sim_data <- simulate_data()
set.seed(43)

# Extracting simulated omic blocks.
sim_blocks <- sim_data$sim_blocks[-4]

# Using fourth block as covariates.
covs <- sim_data$sim_blocks[[4]]


sim_blocks_adj <- cov_adj(sim_blocks,covs,nrow(covs))