Meta Analysis for SNP-Set (Sequence) Kernel Association Test
Example dataset
Generate summary statistics files
Get parameters and residuals from H0
Meta analysis SKAT with summary data from each study cohort.
Meta analysis SKAT with individual level genotype data
Read Meta SSD and Info files
Functions for Meta-analysis Burden Test, Sequence Kernel Association Test (SKAT) and Optimal SKAT (SKAT-O) by Lee et al. (2013) <doi:10.1016/j.ajhg.2013.05.010>. These methods use summary-level score statistics to carry out gene-based meta-analysis for rare variants.