comp_covid_score function

comp_covid_score

Function to compute the COVID severity score made by Nightingale Health UK Biobank Initiative et al. on Nightingale metabolomics data-set.

comp_covid_score(dat, betas = MiMIR::covid_betas, quiet = FALSE)

Arguments

• dat: numeric data-frame with Nightingale-metabolomics
• betas: data.frame containing the coefficients used for the regression of the COVID-score
• quiet: logical to suppress the messages in the console

Returns

data-frame containing the value of the COVID-score on the uploaded data-set

Details

Multivariate model predicting the risk of severe COVID-19 infection. It is based on 37 metabolic features and trained using LASSO regression on 52,573 samples from the UK-biobanks.

Examples

library(MiMIR)

#load the Nightignale metabolomics dataset
metabolic_measures <- synthetic_metabolic_dataset

#Compute the mortality score
mortScore<-comp_covid_score(dat=metabolic_measures, quiet=TRUE)

References

This function is constructed to be able to apply the COVID-score as described in: Nightingale Health UK Biobank Initiative et al. (2021) Metabolic biomarker profiling for identification of susceptibility to severe pneumonia and COVID-19 in the general population. eLife, 10, e63033, doi:10.7554/eLife.63033

See Also

prep_data_COVID_score, covid_betas, comp.mort_score