subset_samples_miss function

subset_samples_miss

Helper function that subsets the NH-metabolomics matrix to the samples with less than Nmax missing values

subset_samples_miss(x, Nmax = 1, quiet = FALSE)

Arguments

• x: numeric data-frame with Nightingale-metabolomics
• Nmax: integer indicating the max number of missing values allowed per sample (N suggested= 1)
• quiet: logical to suppress the messages in the console

Returns

matrix with the samples with limited amount of missing values in the Nightingale-metabolomics dataset

Examples

## Not run:

library(MiMIR)

#load the Nightignale metabolomics dataset
metabolic_measures <- read.csv("Nightingale_file_path",header = TRUE, row.names = 1)
#Select the samples with only 1 missing value
mat <- subset_samples_miss(x=metabolic_measures, Nmax=1)
## End(Not run)

References

This function is constructed to be able to apply the metaboAge as described in: van den Akker Erik B. et al. (2020) Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease. Circulation: Genomic and Precision Medicine, 13, 541-547, doi:10.1161/CIRCGEN.119.002610

See Also

QCprep, apply.fit, subset_metabolites_overlap, subset_samples_zero, subset_samples_sd, impute_miss, apply.scale, and report.dim