Fast and Accurate Trisomy Prediction in Non-Invasive Prenatal Testing
Add a sample to an existing control group
Convert list of nipt samples to nipt control group
Load and bin BAM file
Use an NCV template to calculate a NCV score for sample of interest
Calculate 'standard' Z-score
Performs chi-square based variation reduction
Calculate chromosomal fraction
Diagnose control group
Perform a GC bias correction on nipt sample
Get control chromosomes names
Get all chromosomal fractions of a control group
Get reads per chromosome per control group sample
Best matching control group by least sum of squares
Regression based Z score
Prepare NCV calculation
Remove duplicate samples from control group
Remove a sample by samplename from control group
Retrieve the chromosomal fractions of a chromosome of interest
Fast and Accurate Trisomy Prediction in Non-Invasive Prenatal Testing.