Power in a Group Sequential Design
The O'Brien-Fleming Alpha Spending Function
My Survfit
Stack a dataset
Convert CDF Odds Ratio to Logged Relative Risks
Calender year rates to Study Year Rates
Cumulative-risk ratios to risk ratios
Relative cumulative mortality to Relative Risk
Relative risk to Relative Cumulative Mortality
Lookup values for a piecewise constant function
Mayo Clinic Lung Cancer Data
A utility function for forming differences
Create a subset of a "cpd.PwrGSD" object
Calculate Power in a Group Sequential Design
The Lan-Demets method of Boundary Construction
The Wang-Tsiatis Power Alpha Spending Function
The Pocock Alpha Spending Function
The Stochastic Curtailment method of Boundary Construction
The Haybittle method of Boundary Construction
Create a skeleton compound PwrGSD object
Extract the Power results
Convert a "PwrGSD" object to a "boundaries" object
Plot Method for cpd.PwrGSD objects
Computes efficacy and futility boundaries
Conditional type I and type II error probabilities given current value...
Verifies the results of "GrpSeqBnds" via simulation
Weighted log-rank test
Weighted Integrated Survival function test
Aggregated Hazard
Converts a stochastic curtailment boundary (conditional type I or II e...
A function for computing the probability density for the group sequent...
A function for computing the bias adjusted point estimate for a statis...
Function to extract the 'detail' component from a PwrGSD object
Tools for the evaluation of interim analysis plans for sequentially monitored trials on a survival endpoint; tools to construct efficacy and futility boundaries, for deriving power of a sequential design at a specified alternative, template for evaluating the performance of candidate plans at a set of time varying alternatives. See Izmirlian, G. (2014) <doi:10.4310/SII.2014.v7.n1.a4>.