QTL Genome-Wide Composite Interval Mapping
Process raw data
To insert marker in genotype.
QTL Genome-Wide Composite Interval Mapping
Read raw data
To perform QTL mapping with wang method
The second step of wang method
To perform QTL mapping with Wen method
The second step of Wen method
To perform QTL mapping with Wen method
The second step of Zhou method for multiple environments
The second step of Zhou method for single environment
Conduct multiple quantitative trait loci (QTL) and QTL-by-environment interaction (QEI) mapping via ordinary or compressed variance component mixed models with random- or fixed QTL/QEI effects. First, each position on the genome is detected in order to obtain a negative logarithm P-value curve against genome position. Then, all the peaks on each effect (additive or dominant) curve or on each locus curve are viewed as potential main-effect QTLs and QEIs, all their effects are included in a multi-locus model, their effects are estimated by both least angle regression and empirical Bayes (or adaptive lasso) in backcross and F2 populations, and true QTLs and QEIs are identified by likelihood radio test. See Zhou et al. (2022) <doi:10.1093/bib/bbab596> and Wen et al. (2018) <doi:10.1093/bib/bby058>.