A Fast and Light Package to Compute Polygenic Risk Scores
Download 1000 Genomes Phase III panel
Finding a file in an FTP directory This is an internal function to hel...
Retrieve GWAS summary datasets from GWAS catalog 'gwascat.download t...
Helper function to sum logs without loss of precision
Compute PGS from GWAS summary statistics using Bayesian sum of single-...
Compute PGS from GWAS summary statistics using posteriors from Wakefie...
Compute Standard deviation prior (SD prior) for quantitative traits us...
Estimate trait variance, internal function
Compute posterior probabilities using Wakefield's approximate Bayes Fa...
compute posterior probabilities using Wakefield's approximate Bayes Fa...
Quickly computes polygenic scores from GWAS summary statistics of either case-control or quantitative traits without parameter tuning. Reales,G., Vigorito, E., Kelemen,M., Wallace,C. (2021) <doi:10.1101/2020.07.24.220392> "RápidoPGS: A rapid polygenic score calculator for summary GWAS data without a test dataset".