SEMgraph1.2.4 package

Network Analysis and Causal Inference Through Structural Equation Modeling

alsData

Amyotrophic Lateral Sclerosis (ALS) dataset

ancestry

Node ancestry utilities

clusterGraph

Topological graph clustering

clusterScore

Module scoring

colorGraph

Vertex and edge graph coloring on the base of fitting

cplot

Subgraph mapping

dagitty2graph

Graph conversion from dagitty to igraph

extractClusters

Cluster extraction utility

factor.analysis

Factor analysis for high dimensional data

gplot

Graph plotting with renderGraph

graph2dag

Convert directed graphs to directed acyclic graphs (DAGs)

graph2dagitty

Graph conversion from igraph to dagitty

graph2lavaan

Graph to lavaan model

lavaan2graph

lavaan model to graph

localCI.test

Conditional Independence (CI) local tests of an acyclic graph

mergeNodes

Graph nodes merging by a membership attribute

modelSearch

Optimal model search strategies

orientEdges

Assign edge orientation of an undirected graph

pairwiseMatrix

Pairwise plotting of multivariate data

parameterEstimates

Parameter Estimates of a fitted SEM

pathFinder

Perturbed path search utility

properties

Graph properties summary and graph decomposition

resizeGraph

Interactome-assisted graph re-seizing

SEMace

Compute the Average Causal Effect (ACE) for a given source-sink pair

SEMbap

Bow-free covariance search and data de-correlation

SEMdag

Estimate a DAG from an input (or empty) graph

SEMdci

SEM-based differential network analysis

SEMgsa

SEM-based gene set analysis

SEMpath

Search for directed or shortest paths between pairs of source-sink nod...

SEMrun

Fit a graph as a Structural Equation Model (SEM)

SEMtree

Tree-based structure learning methods

Shipley.test

Missing edge testing implied by a DAG with Shipley's basis-set

summary.GGM

GGM model summary

summary.RICF

RICF model summary

transformData

Transform data methods

weightGraph

Graph weighting methods

Estimate networks and causal relationships in complex systems through Structural Equation Modeling. This package also includes functions for importing, weight, manipulate, and fit biological network models within the Structural Equation Modeling framework as outlined in the Supplementary Material of Grassi M, Palluzzi F, Tarantino B (2022) <doi:10.1093/bioinformatics/btac567>.