SIMMS1.3.2 package

Subnetwork Integration for Multi-Modal Signatures

calculate.meta.survival

Fit a meta-analytic Cox proportional hazards model to a single feature

calculate.network.coefficients

Calculate Cox statistics for input dataset

calculate.sensitivity.stats

Computes sensitivity measures

centre.scale.dataset

Centre and scale a data matrix

create.classifier.multivariate

Trains and tests a multivariate survival model

create.classifier.univariate

Trains and tests a univariate (per subnetwork module) survival model

create.KM.plot

Plots Kaplan-meier survival curve for a given risk grouping & survival...

create.sensitivity.plot

Plots sensitivity analysis for class label dichotomization at supplied...

create.survivalplots

Plots Kaplan-meier survival curves

create.survobj

Utility function for loading meta-analysis lists

derive.network.features

Derive univariate features from pathway-derived networks

dichotomize.dataset

Dichotomize a single dataset

dichotomize.meta.dataset

Dichotomize and unlist a meta-analysis list

fit.coxmodel

Fit a Cox proportional hazards model

fit.interaction.model

Cox model two features separately and together

fit.survivalmodel

Trains a multivariate survival model

get.adjacency.matrix

A utility function to convert tab delimited networks file into adjacen...

get.chisq.stats

Applies survdiff function

get.program.defaults

A utility function to return the inst/ directory of the installed pack...

load.cancer.datasets

Load all cancer meta-analysis datasets

make.matrix

Utility function used by get.adjacency.matrix()

pred.survivalmodel

Apply a multivariate survival model to validation datasets

prepare.training.validation.datasets

Prepare training and validation datasets

SIMMS-package

SIMMS - Subnetwork Integration for Multi-Modal Signatures

Algorithms to create prognostic biomarkers using biological genesets or networks.

  • Maintainer: Syed Haider
  • License: GPL-2
  • Last published: 2022-04-24