Simple Transcriptome Meta-Analysis for Identifying Stress-Responsive Genes
Calculate the Stress Response ratio (SRratio)
Create a Data Frame of SRscore
Aggregate the results of the three functions into a single list
Create a data frame from all combinations between two specified variab...
Find the expression ratio for each experimental sample for the specifi...
Plot the Distribution of SRscore Values
Plot Ranked SRscore Values with Threshold-Based Highlighting
Barplot of Top Genes Ranked by Absolute SRscore
Stress Response score (SRscore) is a stress responsiveness measure for transcriptome datasets and is based on the vote-counting method. The SRscore is determined to evaluate and score genes on the basis of the consistency of the direction of their regulation (Up-regulation, Down-regulation, or No change) under stress conditions across multiple analyzed research projects. This package is based on the HN-score (score based on the ratio of gene expression between hypoxic and normoxic conditions) proposed by Tamura and Bono (2022) <doi:10.3390/life12071079>, and can calculate both the original method and an extended calculation method described in Fukuda et al. (2025) <doi:10.1093/plphys/kiaf105>.