R Functions for Chapter 3,4,6,7,9,10,11,12,14,15 of Sample Size Calculation in Clinical Research
A + B Escalation Design with Dose De-escalation
A + B Escalation Design without Dose De-escalation
Average Bioequivalence
ANOVA with Repeat Measures
Test the Carry-over effect
Cochran-Armitage's Test for Trend
Test for equality in Cox PH model.
Test for Equivalence in Cox PH model.
Test for non-inferiority/superiority in Cox PH model.
Test for Equality of Intra-Subject Variabilities in Crossover Design
Test for Similarity of Intra-Subject Variabilities in Crossover Design
Test for Non-Inferiority/Superiority of Intra-Subject Variabilitie in ...
Williams' Test for Minimum effective dose (MED)
Linear Contrast Test for Binary Dose Response Study
Linear Contrast Test for Dose Response Study
Linear Contrast Test for Time-to-Event Endpoint in dose response study
Test Goodness of Fit by Pearson's Test
Test Goodness of Fit by Pearson's Test for two-way table
Individual Bioequivalence
Test for Equality of Inter-Subject Variabilities
Test for Equality of Inter-Subject Variabilities
Test for Equality of Intra-Subject CVs
Test for Equivalence of Intra-Subject CVs
Test for Non-Inferiority/Superiority of Intra-Subject CVs
Test for Equality of Intra-Subject Variabilities
Test for Similarity of Intra-Subject Variabilities
Test for Non-Inferiority/Superiority of Intra-Subject Variabilities
McNemar Test in 2 by 2 table
Test for Equality in Multiple-Sample William Design
Test for Equivalence in Multiple-Sample William Design
Test for Non-Inferiority/Superiority in Multiple-Sample William Design
Multiple Testing procedures
Test for independence for nonparametric study
One Sample Location problem in Nonparametric
Two sample location problem for Nonparametric
One Sample Mean Test for Equality
One Sample Mean Test for Equivalence
One Sample Mean Test for Non-Inferiority/Superiority
One sample proportion test for equality
One sample proportion test for equivalence
One sample proportion test for Non-inferiority/Superiority
One-Sided Tests with fixed effect sizes
One-Sided Tests with varying effect sizes
Pairwise Comparison for Multiple-Sample One-Way ANOVA
One-way ANOVA pairwise comparison
Population Bioequivalence
Propensity Score ignoring strata
Propensity Score with Stratas
Quality of life
Crossover Design in QT/QTc Studies without covariates
Parallel Group Design in QT/QTc Studies without covariates
Crossover Design in QT/QTc Studies with PK response as covariate
Parallel Group Design in QT/QTc Studies with PK response as covariate
Relative Risk in Parallel Design test for Equality
Relative Risk in Parallel Design test for Equivalence
Relative Risk in Parallel Design test for Non-inferiority/Superiority
Relative Risk in Crossover Design test for Equality
Relative Risk in Crossover Design test for Equivalence
Relative Risk in Crossover Design test for Non-inferiority/Superiority
Calculate the power for Sensitivity Index
Stuart-Maxwell Test
Sample Size calculation in Clinical Research
Two Sample Crossover Design Test for Equality
Two Sample Crossover Design Test for Equivalence
Two Sample Crossover Design Test for Non-Inferiority/Superiority
Two Sample Mean Test for Equality
Two Sample Mean Test for Equivalence
Two Sample Mean Test for Non-Inferiority/Superiority
Two sample proportion test for equality
Two sample proportion test for equivalence
Two sample proportion test for Non-Inferiority/Superiority
Two sample proportion Crossover design test for equality
Two sample proportion Crossover design test for equivalence
Two sample proportion Crossover design for Non-inferiority/Superiority
Test for two sample conditional data in exponential model for survival...
Test for two sample equality in exponential model for survival data
Test for two sample equivalence in exponential model for survival data
Test for two sample Non-Inferiority/Superiority in exponential model f...
Two-Sided Tests with fixed effect sizes
Two-Sided Tests with varying effect sizes
Composite Efficacy Measure(CEM) for Vaccine clinical trials.
The evaluation of vaccine efficacy with Extremely Low Disease Incidenc...
Reduction in Disease Incidence(RDI) for Vaccine clinical trials.
In Vitro Bioequivalence
William Design test for equality
Williams Design test for equivalence
Williams Design test for Non-inferiority/Superiority
Functions and Examples in Sample Size Calculation in Clinical Research.