apmx1.1.1 package

Automated Population Pharmacokinetic Dataset Assembly

cov_apply

Apply covariates to PK(PD) dataset

cov_find

Find covariates of particular types

pk_build

Create a NONMEM PK(PD) dataset

pk_combine

combine study level datasets to form population dataset

pk_define

Create definition file from published dataset

pk_summarize

Produce summary tables for a PK(PD) dataset

pk_write

Write PK(PD) dataset to specified location

variable_list_create

Create a dataframe with standard variable names and definitions

version_log

Create and maintain a dataset version log

Download source packageRead PDF manual

Automated methods to assemble population PK (pharmacokinetic) and PKPD (pharmacodynamic) datasets for analysis in 'NONMEM' (non-linear mixed effects modeling) by Bauer (2019) <doi:10.1002/psp4.12404>. The package includes functions to build datasets from SDTM (study data tabulation module) <https://www.cdisc.org/standards/foundational/sdtm>, ADaM (analysis dataset module) <https://www.cdisc.org/standards/foundational/adam>, or other dataset formats. The package will combine population datasets, add covariates, and create documentation to support regulatory submission and internal communication.

  • Maintainer: Stephen Amori
  • License: GPL (>= 3)
  • Last published: 2024-01-09

Useful links