Genome-Wide RNA Degradation Analysis Using BRIC-Seq Data
BridgeR basic function for calculating RNA half-life from BRIC-seq dat...
BRIC-seq Dataset checker
Calculate relative RPKM expression from data.table format.
Calculate relative RPKM expression from raw data.
Shinyapp reporting for drawing RNA decay curve.
RNA half-life Grubbs test.
Calculate RNA half-life for each gene using 3model method.
Calculate RNA half-life for each gene using R2 selection method.
Calculate the normalized RPKM for BRIC-seq dataset.
Calculate normalization factors for BRIC-seq datasets.
Calculate normalization factors from house-keeping genes.
Calculate Fold-change of RNA half-life and p-value.
BRIC-seq result checker
Calculate RNA half-life SD.
BRIC-seq result dataset for p-value estimation using grubbs test
test BRIC-seq dataset for p-value estimation using grubbs test
BRIC-seq is a genome-wide approach for determining RNA stability in mammalian cells. This package provides a series of functions for performing quality check of your BRIC-seq data, calculation of RNA half-life for each transcript and comparison of RNA half-lives between two conditions.