Simulation of Plasma Caffeine Concentrations by Using Population Pharmacokinetic Model
Create a dataset of the concentration-time curve of single oral admini...
Create a dataset of the concentration-time curve of multiple dosing of...
Calculate descriptive statistics of simulated PK parameters
Calculate a duration of plasma caffeine concentration over specified t...
Create a dataset for simulation of single dose of caffeine
Create a dataset for simulation of multiple dose of caffeine
Create concentration-time curve after single dose of caffeine
Create concentration-time curve after multiple doses of caffeine
Run shiny app to interactively simulate plasma caffeine concentration.
Simulate plasma caffeine concentrations using population pharmacokinetic model described in Lee, Kim, Perera, McLachlan and Bae (2015) <doi:10.1007/s00431-015-2581-x>.