coloc5.2.3 package

Colocalisation Tests of Two Genetic Traits

annotate_susie

annotate susie_rss output for use with coloc_susie

approx.bf.estimates

Internal function, approx.bf.estimates

approx.bf.p

Internal function, approx.bf.p

bin2lin

binomial to linear regression conversion

check_alignment

check alignment

check_dataset

check_dataset

coloc-package

Colocalisation tests of two genetic traits

coloc.abf

Fully Bayesian colocalisation analysis using Bayes Factors

coloc.bf_bf

Coloc data through Bayes factors

coloc.detail

Bayesian colocalisation analysis with detailed output

coloc.process

Post process a coloc.details result using masking

coloc.signals

Coloc with multiple signals per trait

coloc.susie

run coloc using susie to detect separate signals

coloc.susie_bf

run coloc using susie to detect separate signals

combine.abf

combine.abf

est_cond

generate conditional summary stats

estgeno1

estgeno1

find.best.signal

Pick out snp with most extreme Z score

findends

trim a dataset to central peak(s)

findpeaks

trim a dataset to only peak(s)

finemap.abf

Bayesian finemapping analysis

finemap.bf

Finemap data through Bayes factors

finemap.signals

Finemap multiple signals in a single dataset

logbf_to_pp

logbf 2 pp

logdiff

logdiff

logsum

logsum

map_cond

find the next most significant SNP, conditioning on a list of sigsnps

map_mask

find the next most significant SNP, masking a list of sigsnps

plot-methods

plot a coloc_abf object

plot_dataset

plot a coloc dataset

print-methods

print.coloc_abf

process.dataset

process.dataset

runsusie

Run susie on a single coloc-structured dataset

sdY.est

Estimate trait variance, internal function

sensitivity

Prior sensitivity for coloc

subset_dataset

subset_dataset

Var.data.cc

Var.data

Var.data

Var.data

Performs the colocalisation tests described in Giambartolomei et al (2013) <doi:10.1371/journal.pgen.1004383>, Wallace (2020) <doi:10.1371/journal.pgen.1008720>, Wallace (2021) <doi:10.1371/journal.pgen.1009440>.

  • Maintainer: Chris Wallace
  • License: GPL
  • Last published: 2023-10-03