cvasi1.5.0 package

Calibration, Validation, and Simulation of TKTD Models

plot_ppc

Creates a PPC plot for a single dataset

plot_scenario

Creates a prediction plot for one effect scenario

plot_sd

Creates plot of model results (uncertainties optional)

plot.param_space

Plot profiled parameter space

plot

S3 plotting functions

pull_metadata

Pull metadata from scenarios

Scenarios

Effect scenario classes

num_info

Print information about numerical solver result

parameter_set

Set of model parameters

pipe

Pipe operator

pll_debug

Disable parallelization for debugging

plot_epx

Plot EPx values

plot_ppc_combi

Create PPC plot for one or more datasets

sequence.extract

Extract and replace elements of a sequence

set_param

Set scenario parameters

set_tag

Set a tag

set_times

Set output times

set_transfer

Set transfer events

set_window

Set window length

Magma-class

Magma scenario class

Magma

Magma model (Witt et al., submitted)

no_exposure

Zero exposure

set_noexposure

Set zero exposure

is_guts

Test if argument is a GUTS scenario

is_lemna

Test if argument is a Lemna scenario

is_LemnaThreshold

Test if argument is a LemnaThreshold scenario

is_scenario

Test if argument is an effect scenario

Lemna_Schmitt

Lemna model (Schmitt et al. 2013)

Algae_Simple

Simple algae model without environment (Rendal et al. 2023)

Algae_TKTD

Algae model variant (Weber et al. 2012) with scaled damage

Algae_Weber

Algae model, SAM-X (Weber et al. 2012)

Lemna_SETAC

Lemna model v1.3 (Klein et al. 2021)

Algae-models

Algae models

batch

Batch simulation of multiple exposure levels

cache_controls

Cache control simulations

calibrate

Fit model parameters to experimental data

CalibrationSet

Calibration set

ci_from_hessian

Parameter confidence intervals from fit

DEB_abj

DEB_abj

DEB-models

Dynamic Energy Budget (DEB) models

DEBtox

DEBtox model

diagnostics

Diagnostics of solvers

dose_response

Calculate a dose response curve

effect

Effect level

epx_mtw

Calculate EPx values for a series of moving time window

epx

Effect profiles (EPx values)

explore_space

Explore parameter space

ExposureSeries

Exposure time-series

fit_growth

Fit growth parameters

fit_tktd

Fit TK/TD parameters

fx

Generic to calculate effects for a particular scenario

get_model

Get model name

get_param

Get scenario parameters

get_tag

Get scenario tag

get_times

Get output times

GUTS_IT

GUTS-IT scenario

GUTS_RED_IT

GUTS-RED-IT scenario

GUTS_RED_SD

GUTS-RED-SD scenario

GUTS_SD

GUTS-SD scenario

GUTS-RED-models

GUTS-RED models

import_morse

Import morse model parameters

import_swash

SWASH project exposure profile import

import_toxswa

Import TOXSWA exposure series

is_deb

Test if argument is a DEB scenario

Lemna-models

Lemna models

lik_profile

Likelihood profiling

log_enable

Start and stop logging

log_envir

Log R environment properties

log_lik

Calculate log likelihood

log_msg

Add a log message

log_scenarios

Log scenario properties

Macrophyte-models

Macrophyte models

sequence

Sequence of scenarios

set_bounds

Set boundaries of model parameters

set_endpoints

Set effect endpoints

set_exposure

Set exposure time-series

set_forcings

Set time-dependent parameters

set_init

Set initial state

set_mode_of_action

Set mode of action

simulate_batch

Batch simulation using multiple exposure series

simulate

Simulate an effect scenario

solver

Calls ODE solver for a particular model

survival

Survival rate

td2cs

Create calisets from tox_data

tox_data

Prepare ecotox study data for fitting

Transferable

Biomass transfer class

Eases the use of ecotoxicological effect models. Can simulate common toxicokinetic-toxicodynamic (TK/TD) models such as General Unified Threshold models of Survival (GUTS) and Lemna. It can derive effects and effect profiles (EPx) from scenarios. It supports the use of 'tidyr' workflows employing the pipe symbol. Time-consuming tasks can be parallelized.

  • Maintainer: Nils Kehrein
  • License: GPL (>= 3)
  • Last published: 2025-09-11