Estimate ED50 and Its Confidence Interval
Estimate Confidence Interval of ED50 Using Isotonic Regression
Isotonic Regression Function
The resample function of isotonic regression
Compare ED50 Estimation of Independent Two-sample Case
Estimate ED50
Generate Simulation Data of Up-and-Down Experiment
Covert Data Using PAVA Algorithm
Functions of five estimation method for ED50 (50 percent effective dose) are provided, and they are respectively Dixon-Mood method (1948) <doi:10.2307/2280071>, Choi's original turning point method (1990) <doi:10.2307/2531453> and it's modified version given by us, as well as logistic regression and isotonic regression. Besides, the package also supports comparison between two estimation results.