Evidential Analysis of Genetic Association Data
Genotype coding adjusement
Profile likelihood calculation using regression models
Profile likelihood calculation using regression models
Plot profile likelihood density for a single SNP.
Evidential analysis for genetic data using regression models
Example map data for evian_binary_raw.
Example dataset with a binary outcome.
Example map data for evian_linear_raw.
Example dataset with a quantative outcome.
A recursive function that expands the grid search for MLE.
Obtain the range of the grid where MLE will be searched at
Generalized Likelihood Ratio test
Plot methods for multiple glr result in a genomic region.
Plot methods for multiple likelihood intervals in a genomic region.
Robust adjustment function
interior subsetting function
Evidential regression analysis for dichotomous and quantitative outcome data. The following references described the methods in this package: Strug, L. J., Hodge, S. E., Chiang, T., Pal, D. K., Corey, P. N., & Rohde, C. (2010) <doi:10.1038/ejhg.2010.47>. Strug, L. J., & Hodge, S. E. (2006) <doi:10.1159/000094709>. Royall, R. (1997) <ISBN:0-412-04411-0>.