Estimation of (Local) False Discovery Rates and Higher Criticism
Fit Null Distribution To Censored Data by Maximum Likelihood
Distribution of the Vanishing Correlation Coefficient (rho=0) and Rela...
Internal fdrtool Functions
Estimate (Local) False Discovery Rates For Diverse Test Statistics
Greatest Convex Minorant and Least Concave Majorant
Grenander Estimator of a Decreasing or Increasing Density
The Half-Normal Distribution
Compute Empirical Higher Criticism Scores and Corresponding Decision T...
Monotone Regression: Isotonic Regression and Antitonic Regression
Estimate the Proportion of Null p-Values
Estimates both tail area-based false discovery rates (Fdr) as well as local false discovery rates (fdr) for a variety of null models (p-values, z-scores, correlation coefficients, t-scores). The proportion of null values and the parameters of the null distribution are adaptively estimated from the data. In addition, the package contains functions for non-parametric density estimation (Grenander estimator), for monotone regression (isotonic regression and antitonic regression with weights), for computing the greatest convex minorant (GCM) and the least concave majorant (LCM), for the half-normal and correlation distributions, and for computing empirical higher criticism (HC) scores and the corresponding decision threshold.