Group Response Adaptive Randomization for Clinical Trials
Bai Hu Shen's Urn
Birth and Death Urn
Complete Randomization
Hu and Zhang's Doubly Biased Coin Design with Binary Response Type
Hu and Zhang's Doubly Biased Coin Design with Continuous Response Type
Drop the loser rule
Hu and Zhang's Doubly Biased Coin Deisgn with delayed Binary Response
Hu and Zhang's Doubly Biased Coin Deisgn with delayed Continuous Respo...
Generalized drop-the-loser rule
Group Doubly Biased Coin Design with Delayed Discrete Response
Group Doubly Biased Coin Design with Continuous Response Type
Group Doubly Biased Coin Design with Binary Response Type
Group Doubly Biased Coin Design with Delayed Continuous Response
grouprar-package: Group Response-Adaptive Randomization for Clinical T...
Randomized Pólya urn procedure
Randomized Play-the-winner Rule
Randomized Play-the-winner rule with multiple arms ()
Implement group response-adaptive randomization procedures, which also integrates standard non-group response-adaptive randomization methods as specialized instances. It is also uniquely capable of managing complex scenarios, including those with delayed and missing responses, thereby expanding its utility in real-world applications. This package offers 16 functions for simulating a variety of response adaptive randomization procedures. These functions are essential for guiding the selection of statistical methods in clinical trials, providing a flexible and effective approach to trial design. Some of the detailed methodologies and algorithms used in this package, please refer to the following references: LJ Wei (1979) <doi:10.1214/aos/1176344614> L. J. WEI and S. DURHAM (1978) <doi:10.1080/01621459.1978.10480109> Durham, S. D., FlournoY, N. AND LI, W. (1998) <doi:10.2307/3315771> Ivanova, A., Rosenberger, W. F., Durham, S. D. and Flournoy, N. (2000) <https://www.jstor.org/stable/25053121> Bai Z D, Hu F, Shen L. (2002) <doi:10.1006/jmva.2001.1987> Ivanova, A. (2003) <doi:10.1007/s001840200220> Hu, F., & Zhang, L. X. (2004) <doi:10.1214/aos/1079120137> Hu, F., & Rosenberger, W. F. (2006, ISBN:978-0-471-65396-7). Zhang, L. X., Chan, W. S., Cheung, S. H., & Hu, F. (2007) <https://www.jstor.org/stable/26432528> Zhang, L., & Rosenberger, W. F. (2006) <doi:10.1111/j.1541-0420.2005.00496.x> Hu, F., Zhang, L. X., Cheung, S. H., & Chan, W. S. (2008) <doi:10.1002/cjs.5550360404>.