Group Sequential Refined Secondary Boundary
Lower and Upper Bounds Generator
Correlation Matrix Generator
Find the Location of Maximum, Standard OBF and POC
Find the Location of Maximum, Error Spending Approach
Calculate Nominal Significance, Error Spending Approach
Calculate Primary Boundaries, the Error Spending Approach
Difference between the Error Rate and Significance Level, the Error Sp...
Calculate Refined Secondary Boundary, Error Spending Approach
Calculate Nominal Significance, Standard Approach
Calculate Primary Boundaries, Standard Approach
Calculate the Primary Boundaries
Summarize Primary and Refined Secondary Boundaries in a TeX table
Summarize Primary and Refined Secondary Boundaries, Nominal Significan...
Difference between the Error Rate and Significance Level, Standard App...
Calculate the Refined Secondary Boundaries, Standard OBF and POC
Calculate Refined Secondary Boundaries and Nominal Significance
Calculate Refined Secondary Boundaries and Nominal Significance, the E...
Calculate Refined Secondary Boundaries and Nominal Significance, Stand...
A gate-keeping procedure to test a primary and a secondary endpoint in a group sequential design with multiple interim looks. Computations related to group sequential primary and secondary boundaries. Refined secondary boundaries are calculated for a gate-keeping test on a primary and a secondary endpoint in a group sequential design with multiple interim looks. The choices include both the standard boundaries and the boundaries using error spending functions. See Tamhane et al. (2018), "A gatekeeping procedure to test a primary and a secondary endpoint in a group sequential design with multiple interim looks", Biometrics, 74(1), 40-48.