rewire_network function

Rewires interactions in a pathway, which go through a gene not represented by any SNPs in the considered GWASdata dataset.

## S4 method for signature 'pathway'
rewire_network(object, x)

Arguments

• object: pathway object which's network matrix will be rewired
• x: A vector of gene names, indicating which genes are not represented by SNPs in the considered GWASdata object and will be removed

Returns

A pathway object including the rewired network matrix

Examples

## Not run:

data(hsa04020)
summary(hsa04020)
hsa04020_rewired <- rewire_network(hsa04020, x=c('ADCY3', 'CALML3','GNAQ'))
summary(hsa04020_rewired)
## End(Not run)

Author(s)

Juliane Manitz, Stefanie Friedrichs