Nonlinear Mixed Effects Models in Population PK/PD
Add CWRES
NPDE calculation for nlmixr2
Add table information to nlmixr2 fit object without tables
Control for bobyqa estimation method in nlmixr2
Produce delta objective function for boostrap
Bootstrap nlmixr2 fit
Stepwise Covariate Model-selection (SCM) method
Control Options for FOCEi
Control for lbfgsb3c estimation method in nlmixr2
Control for n1qn1 estimation method in nlmixr2
Control for newuoa estimation method in nlmixr2
nlmixr2 defaults controls for nlm
Control Values for nlme Fit with extra options for nlmixr
nlmixr2 nlminb defaults
nlmixr2 fits population PK and PKPD non-linear mixed effects models.
Check your nlmixr2 installation for potential issues
nlmixr2 defaults controls for nls
nlmixr2 optim defaults
Linearly re-parameterize the model to be less sensitive to rounding er...
Estimate the objective function values for a model while fixing define...
Estimate the objective function values for a model while fixing define...
Profile confidence intervals with log-likelihood profiling
Objects exported from other packages
Control Options for SAEM
Set/get Objective function type for a nlmixr2 object
Output table/data.frame options
Produce trace-plot for fit if applicable
Control for uobyqa estimation method in nlmixr2
VPC based on ui model
VPC based on ui model
VPC based on ui model
VPC based on ui model
VPC simulation
Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).
Useful links