Nonlinear Mixed Effects Models in Population PK/PD, Data
1 Compartment Model Simulated Data from ACOP 2016
1 Compartment Model w/ Michaelis-Menten Elimination
2 Compartment Model
2 Compartment Model with Michaelis-Menten Clearance
1 Compartment Model Simulated Data from ACOP 2016
1 Compartment Model w/MM elimination Simulated Data from ACOP 2016
2 Compartment Model with Infusion Simulated Data from ACOP 2016
2 Compartment Model w/MM elimination Simulated Data from ACOP 2016
Inverse Guassian absorption model
Mavoglurant PK data
Parent/Metabolite dataset
Nimotuzumab PK data
One compartment test dataset showing NONMEM 7.4.3 output
1 Compartment Model with Oral Absorption Simulated Data from ACOP 2016
1 Compartment Model w/ Oral Absorption & Michaelis-Menten Elimination
2 Compartment Model with Oral Absorption Simulated Data from ACOP 2016
1 Compartment Model w/ Oral Absorption & Michaelis-Menten Elimination
Single Dose Phenobarbitol PK/PD
Pump failure example dataset
Pregnant Rat Diet Experiment
Multiple dose theophylline PK data
Multiple dose theophylline PK data
Simulated Data Set for comparing objective functions
Warfarin PK/PD data
Simulated Friberg Myelosuppression model (Yuan Xiong)
Datasets for 'nlmixr2' and 'rxode2'. 'nlmixr2' is used for fitting and comparing nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).
Useful links