Converts 'NONMEM' Models to 'rxode2'
Convert a model to a nonmem2rx model
Autoplot nonmem2rx object
Read in data file
Reads the NONMEM .ext
file for final parameter information
Get the most accurate information you can get from NONMEM
Reads the NONMEM .lst
file for final parameter information
Read nonmem table file
Read a nonmem xml and create output similar to the nmlst()
Get the xml for debugging (without including data etc)
Convert a NONMEM source file to a rxode model (nlmixr2-syle)
Record handling for nonmem records
Objects exported from other packages
'NONMEM' has been a tool for running nonlinear mixed effects models since the 80s and is still used today (Bauer 2019 <doi:10.1002/psp4.12404>). This tool allows you to convert 'NONMEM' models to 'rxode2' (Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>) and with simple models 'nlmixr2' syntax (Fidler et al (2019) <doi:10.1002/psp4.12445>). The 'nlmixr2' syntax requires the residual specification to be included and it is not always translated. If available, the 'rxode2' model will read in the 'NONMEM' data and compare the simulation for the population model ('PRED') individual model ('IPRED') and residual model ('IWRES') to immediately show how well the translation is performing. This saves the model development time for people who are creating an 'rxode2' model manually. Additionally, this package reads in all the information to allow simulation with uncertainty (that is the number of observations, the number of subjects, and the covariance matrix) with a 'rxode2' model. This is complementary to the 'babelmixr2' package that translates 'nlmixr2' models to 'NONMEM' and can convert the objects converted from 'nonmem2rx' to a full 'nlmixr2' fit.