Optimal Block Designs for Two-Colour cDNA Microarray Experiments
Computes the treatment information matrix
Sets parametric values
Creates the graphical layout of resultant optimal design
Generates initial connected block design
Creates the main menu tcltk window
Internal functions
Optimal block designs for two-colour cDNA microarray experiments
Computes A-, MV-, D- and E-optimal or near-optimal block designs for two-colour cDNA microarray experiments using the linear fixed effects and mixed effects models where the interest is in a comparison of all possible elementary treatment contrasts. The algorithms used in this package are based on the treatment exchange and array exchange algorithms of Debusho, Gemechu and Haines (2018) <doi:10.1080/03610918.2018.1429617>. The package also provides an optional method of using the graphical user interface (GUI) R package tcltk to ensure that it is user friendly.