Optimal Row-Column Designs for Two-Colour cDNA Microarray Experiments
Computes the treatment information matrix
Sets parametric values
Creates the graphical layout of resultant optimal row-column design
Generates initial connected row-column design
Creates the main menu tcltk window
Internal functions
Optimal row-column designs for two-colour cDNA microarray experiments
Computes A-, MV-, D- and E-optimal or near-optimal row-column designs for two-colour cDNA microarray experiments using the linear fixed effects and mixed effects models where the interest is in a comparison of all pairwise treatment contrasts. The algorithms used in this package are based on the array exchange and treatment exchange algorithms adopted from Debusho, Gemechu and Haines (2018) <doi:10.1080/03610918.2018.1429617> algorithms after adjusting for the row-column designs setup. The package also provides an optional method of using the graphical user interface (GUI) R package tcltk to ensure that it is user friendly.