Optimal Row-Column Designs for Two-Colour cDNA Microarray Experiments
Computes the treatment information matrix
Sets parametric values
Creates the graphical layout of resultant optimal row-column design
Generates initial connected row-column design
Creates the main menu tcltk window
Internal functions
Optimal row-column designs for two-colour cDNA microarray experiments
Computes A-, MV-, D- and E-optimal or near-optimal row-column designs for two-colour cDNA microarray experiments using the linear fixed effects and mixed effects models where the interest is in a comparison of all pairwise treatment contrasts. The algorithms used in this package are based on the array exchange and treatment exchange algorithms adopted from Debusho, Gemechu and Haines (2016, unpublished) algorithms after adjusting for the row-column designs setup. The package also provides an optional method of using the graphical user interface (GUI) R package tcltk to ensure that it is user friendly.