penPHcure1.0.2 package

Variable Selection in PH Cure Model with Time-Varying Covariates

Implementation of the semi-parametric proportional-hazards (PH) of Sy and Taylor (2000) <doi:10.1111/j.0006-341X.2000.00227.x> extended to time-varying covariates. Estimation and variable selection are based on the methodology described in Beretta and Heuchenne (2019) <doi:10.1080/02664763.2018.1554627>; confidence intervals of the parameter estimates may be computed using a bootstrap approach. Moreover, data following the PH cure model may be simulated using a method similar to Hendry (2014) <doi:10.1002/sim.5945>, where the event-times are generated on a continuous scale from a piecewise exponential distribution conditional on time-varying covariates.

  • Maintainer: Alessandro Beretta
  • License: GPL-2 | GPL-3
  • Last published: 2019-12-03