calculate_individual_shrinkage function

calculate_individual_shrinkage

Calculate the individual eta-shrinkage

Definition: ieta_shr = (var(eta) / omega)

calculate_individual_shrinkage(
  model,
  parameter_estimates,
  individual_estimates_covariance
)

Arguments

• model: (Model) Pharmpy model
• parameter_estimates: (array) Parameter estimates of model
• individual_estimates_covariance: (data.frame) Uncertainty covariance matrices of individual estimates

Returns

(DataFrame) Shrinkage for each eta and individual

Examples

## Not run:

model <- load_example_model("pheno")
results <- load_example_modelfit_results("pheno")
pe <- results$parameter_estimates
covs <- results$individual_estimates_covariance
calculate_individual_shrinkage(model, pe, covs)
## End(Not run)

See Also

calculate_eta_shrinkage