Designing Population PDX Studies
Simulation of a single population PDX experiment
Function to return the mode of a vector of values
Function to calculate the number of false calls for a design for a go-...
Function to calculate the number of missed calls for a design for a go...
Function to summarise the results for a single simulation representing...
Function to run simulations to mimic population PDX studies for a defi...
A function to visualise the false postive rate as a function of PDXn a...
A function to visualise the sensitivity as a function of PDXn and PDXr
Function populationPDXdesignApp
'shiny' app server function
'shiny' app user interface function
Function to run simulations to mimic population PDX studies for variet...
Run simulations to assess the impact of various designs features and the underlying biological behaviour on the outcome of a Patient Derived Xenograft (PDX) population study. This project can either be deployed to a server as a 'shiny' app or installed locally as a package and run the app using the command 'populationPDXdesignApp()'.