Analyses of Protein Post-Translational Modifications
Check that Internet Resource Work Properly and Fail Gracefully When No...
Check Residue a Fixed Position
List Proteins Found in MetOSite Matching a Keyword
Scans a Protein in Search of MetO Sites
Residue Found at the Requested Position
Amino Acid Composition
Find Full Paths to Executables
Get Web Resource
Import a Protein Sequence from a Database
Search for Specific MetO Sites
Compute Euclidean Distances
Compute Distances to the Closest Aromatic Residues
Compute Geometric Parameters of S-Aromatic Motifs
Search for S-Aromatic Motifs
Compute Cross Product
Contains utilities for the analysis of post-translational modifications (PTMs) in proteins, with particular emphasis on the sulfoxidation of methionine residues. Features include the ability to download, filter and analyze data from the sulfoxidation database 'MetOSite'. Utilities to search and characterize S-aromatic motifs in proteins are also provided. In addition, functions to analyze sequence environments around modifiable residues in proteins can be found. For instance, 'ptm' allows to search for amino acids either overrepresented or avoided around the modifiable residues from the proteins of interest. Functions tailored to test statistical hypothesis related to these differential sequence environments are also implemented. Further and detailed information regarding the methods in this package can be found in (Aledo (2020) <https://metositeptm.com>).