Linked Inference of Genomic Experimental Relationships
Align factor loadings to get final integration
Converting other classes of data to a liger object
Converting other classes of data to a ligerDataset object
Calculate agreement metric after integration
Calculate alignment metric after integration
Calculate adjusted Rand index (ARI) by comparing two cluster labeling ...
Calculate a dataset-specificity score for each factor
Calculate Normalized Mutual Information (NMI) by comparing two cluster...
Calculate purity by comparing two cluster labeling variables
Align factor loading by centroid alignment (beta)
Close all links (to HDF5 files) of a liger object
Check difference of two liger command
Convert old liger object to latest version
Access ligerSpatialDataset coordinate data
Create on-disk ligerDataset Object
Create liger object
Create in-memory ligerDataset object
Generate dot plot from input matrix with ComplexHeatmap
Produce single violin plot with data frame passed from upstream
Generic ggplot theme setting for rliger package
Produce single scatter plot with data frame passed from upstream
General heatmap plotting with prepared matrix and data.frames
Downsample datasets
Export predicted gene-pair interaction
Find shared and dataset-specific markers
Calculate proportion mitochondrial contribution
Apply function to chunks of H5 data in ligerDataset object
Import prepared dataset publically available
Impute the peak counts from gene expression data referring to an ATAC ...
Check if given liger object if under new implementation
Check if a liger or ligerDataset object is made of HDF5 file
liger class
Find DEG between groups
Subclass of ligerDataset for ATAC modality
ligerCommand object: Record the input and time of a LIGER function cal...
ligerDataset class
Subclass of ligerDataset for Methylation modality
Subclass of ligerDataset for RNA modality
Subclass of ligerDataset for Spatial modality
Convert between liger and Seurat object
Linking genes to putative regulatory elements
Louvain algorithm for community detection
Fast calculation of feature count matrix
Export predicted gene-pair interaction
Generate a river (Sankey) plot
Create new variable from categories in cellMeta
Merge hdf5 files
Merge matrices while keeping the union of rows
Return preset modality of a ligerDataset object or that of all dataset...
Normalize raw counts data
Perform online iNMF on scaled datasets
Perform iNMF on scaled datasets
Perform factorization for new data
Perform factorization for new value of k
Perform factorization for new lambda value
Perform factorization for subset of data
Access ligerATACDataset peak data
Create barcode-rank plot for each dataset
Generate violin/box plot(s) using liger object
Make dot plot of factor loading in cell groups
Make dot plot of gene expression in cell groups
Create violin plot for multiple genes grouped by clusters
Create density plot basing on specified coordinates
Generate scatter plot(s) using liger object
Create volcano plot with EnhancedVolcano
Visualize factor expression and gene loading
Visualize GO enrichment test result in dot plot
Comprehensive group splited cluster plot on dimension reduction with p...
Plot Heatmap of Gene Expression or Factor Loading
Create heatmap for showing top marker expression in conditions
Create heatmap for pairwise DEG analysis result
Visualize proportion across two categorical variables
Box plot of cluster proportion in each dataset, grouped by condition
Make Riverplot/Sankey diagram that shows label mapping across datasets
Visualize a spatial dataset
Plot the variance vs mean of feature expression
Visualize gene expression or cell metadata with violin plot
Create volcano plot for Wilcoxon test result
Quantile align (normalize) factor loading
Quantile align (normalize) factor loadings
Quantile Align (Normalize) Factor Loadings
Load in data from 10X
Read 10X cellranger files (matrix, barcodes and features) into R sessi...
Read 10X HDF5 file
Read matrix from H5AD file
Read liger object from RDS file
See downsample
Objects exported from other packages
Remove missing cells or features from liger object
Restore links (to HDF5 files) for reloaded liger/ligerDataset object
Retrieve a single matrix of cells from a slot
Create "scaled data" for DNA methylation datasets
Deprecated functions in package rliger
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rliger: Linked Inference of Genomic Experimental Relationships
Perform consensus iNMF on scaled datasets
SNN Graph Based Community Detection
General QC for liger object
Run Gene Ontology enrichment analysis on differentially expressed gene...
Analyze biological interpretations of metagene
Perform iNMF on scaled datasets
Integrate scaled datasets with iNMF or variant methods
Perform online iNMF on scaled datasets
Perform t-SNE dimensionality reduction
Perform Mosaic iNMF (UINMF) on scaled datasets with unshared features
Perform UMAP Dimensionality Reduction
Scale genes by root-mean-square across cells
Batch-aware highly variable gene selection
Select a subset of informative genes
Select variable genes from one dataset with Seurat VST method
Subset liger with brackets
Subset ligerDataset object
Get cell metadata variable
Subset liger object
Subset ligerDataset object
Suggest optimal K value for the factorization
Update old liger object to up-to-date structure
Write in-memory data into H5 file
Write liger object to H5AD files
Uses an extension of nonnegative matrix factorization to identify shared and dataset-specific factors. See Welch J, Kozareva V, et al (2019) <doi:10.1016/j.cell.2019.05.006>, and Liu J, Gao C, Sodicoff J, et al (2020) <doi:10.1038/s41596-020-0391-8> for more details.