zeroRe function

Set random effects and residual error to zero

zeroRe(object, which = c("omega", "sigma"), fix = TRUE)

Arguments

• object: The model to modify
• which: The types of parameters to set to zero
• fix: Should the parameters be fixed to the zero value?

Returns

The object with some parameters set to zero

Examples

one.compartment <- function() {
  ini({
    tka <- log(1.57); label("Ka")
    tcl <- log(2.72); label("Cl")
    tv <- log(31.5); label("V")
    eta.ka ~ 0.6
    eta.cl ~ 0.3
    eta.v ~ 0.1
    add.sd <- 0.7
  })
  model({
    ka <- exp(tka + eta.ka)
    cl <- exp(tcl + eta.cl)
    v <- exp(tv + eta.v)
    d/dt(depot) = -ka * depot
    d/dt(center) = ka * depot - cl / v * center
    cp = center / v
    cp ~ add(add.sd)
  })
}
zeroRe(one.compartment)

See Also

Other Initial conditions: ini.rxUi()

Author(s)

Bill Denney