scaRabee toolkit
Framework for Pharmacokinetic-Pharmacodynamic Model Simulation and Optimization package
Package: | scaRabee |
Type: | Package |
Version: | 1.1-4 |
Date: | 2022-02-04 |
License: | GPL-v3 |
LazyLoad: | yes |
scaRabee
is a toolkit for modeling and simulation primarily intended for the field of pharmacometrics. This package is a R port of Scarabee, a Matlab-based piece of software developed as a fairly simple application for the simulation and optimization of pharmacokinetic and/or pharmacodynamic models specified with explicit solutions, ordinary or delay differential equations.
The method of optimization used in scaRabee is based upon the Nelder-Mead simplex algorithm, as implemented by the fminsearch
function from the neldermead
package.
Please, refer to the vignette to learn how to run analyses with scaRabee
and read more about the methods used in scaRabee
.
scaRabee
is available on the Comprehensive R Archive Network and also at: https://github.com/sbihorel/scaRabee
Sebastien Bihorel (sb.pmlab@gmail.com )
neldermead
Useful links